Benzamidine Sepharose™ 4 Fast Flow (High Sub) is a tool for removal and/or purification of trypsin and trypsin-like serine proteases, as well as zymogens, including urokinase and prekallikrein.
- p-aminobenzamidine (pABA) immobilised on Sepharose™ 4 Fast Flow matrix gives high productivity, and allows easy scale-up
- Effective removal of thrombin and Factor Xa after tag cleavage of recombinant proteins
Removal of serine proteases is easily done directly from serum, monoclonal cell supernatants and bacterial lysates. Benzamidine Sepharose™ 4 Fast Flow (High Sub) is based on highly cross-linked 4% agarose enabling high flow rates without losing binding capacity.