Anti-ITGAX Mouse Monoclonal Antibody [clone: 3.9]

Supplier: Tonbo Biosciences
70-0116-U100EA 51.9 EUR
70-0116-U100
Anti-ITGAX Mouse Monoclonal Antibody [clone: 3.9]
Antibodies
The 3.9 antibody reacts with human CD11c, also known as integrin alpha X. This 150 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha X (CD11c) assembles with Integrin beta-2 (CD18) into a receptor known as CR4 which can bind and induce signaling through ICAMs and VCAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.

Type: Primary
Antigen: ITGAX (integrin, alpha X (complement component 3 receptor 4 subunit))
Clonality: monoclonal
Clone: 3.9
Conjugation: unconjugated
Epitope:
Host: Mouse
Isotype: IgG1 Kappa
Reactivity:
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