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Anti-MSH6 Mouse Monoclonal Antibody [clone: 3A10H7]

Supplier: Thermo Scientific
MA5-15392 targets MSH6 in WB applications and shows reactivity with Human samples. The MA5-15392 immunogen is purified recombinant fragment of MSH6 expressed in E. Coli. <br>. This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer and endometrial cancer.

Type: Primary
Antigen: MSH6
Clonality: Monoclonal
Clone: 3A10H7
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human



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Size Pk VWR Catalog Number Quantity
100 µL 100 µl PIEAMA515392 Blocked
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SPECIFICATIONS

Antigen symbol MSH6
Antigen name MutS homolog 6
Reactivity Human
Conjugation Unconjugated
Clonality Monoclonal
Antibody type Primary
Clone 3A10H7
Host Mouse
Isotype IgG1
Western Blot Yes
Antigen synonyms HNPCC5, GTBP, MSH6, HSAP
Gene ID 2956
Format ascites
Immunogen Purified recombinant fragment of MSH6 expressed in E. Coli.
Form Liquid
Storage Buffer ascites, 0.03% sodium azide
Storage temperature Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Temperature Ice
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