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Anti-CAMP Mouse Monoclonal Antibody [clone: 9H4C4]

Supplier: Thermo Scientific
MA5-15393 targets cAMP in ELISA applications. The MA5-15393 immunogen is cAMP conjugated to KLH. Cyclic adenosine monophosphate (cAMP) plays a key role as an intracellular second messenger for transduction events that follow a number of extracellular signals. The G-Protein Coupled Receptors (GPCR) is the largest family of cell surface receptors. They can be activated by different ligands, such as neurotransmitters, hormones, ions, small molecules, peptides, and other physiological signaling molecules. Typically, the binding of the ligands to its receptor resulting in the activation of G-proteins, in return, activates the effector adenylyl cyclase evoking the production of cAMP. The activation of a protein kinase by cAMP results in the phosphorylation of substrate proteins. Currently successful drugs in marketing have been developed to target these receptors. Among the GPCRs, ~367 receptors are potential drug development targets, but only about 20 have been used to generate therapeutically and commercially successful drugs so far. Because the involvement of cAMP can amplify the response of the ligand binding, the second messenger cAMP has been largely employed to monitor the activation of the GPCR to facilitate the therapeutic drug discovery

Type: Primary
Antigen: CAMP
Clonality: Monoclonal
Clone: 9H4C4
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Chemical



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Size Pk VWR Catalog Number Quantity
100 µL 100 µl PIEAMA515393 Blocked
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SPECIFICATIONS

Antigen symbol CAMP
Antigen name Cathelicidin
Reactivity Chemical
Conjugation Unconjugated
Clonality Monoclonal
Antibody type Primary
Clone 9H4C4
Host Mouse
Isotype IgG1
ELISA Yes
Antigen synonyms Cyclic AMP
Format ascites
Immunogen cAMP, conjugated to KLH
Form Liquid
Storage Buffer ascites, 0.03% sodium azide
Storage temperature Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Temperature Ice
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