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Anti-FBLN5 Mouse Monoclonal Antibody [clone: 1G6A4]

Supplier: Thermo Scientific
MA5-15395 targets FBLN5 in IHC and WB applications and shows reactivity with Human samples. The MA5-15395 immunogen is purified recombinant fragment of FBLN5 (aa242-448) expressed in E. Coli.<br>. The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I , and age-related macular degeneration type 3 .

Type: Primary
Antigen: FBLN5
Clonality: Monoclonal
Clone: 1G6A4
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human



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Size Pk VWR Catalog Number Quantity
100 µL 100 µl PIEAMA515395 Blocked
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SPECIFICATIONS

Antigen symbol FBLN5
Antigen name Fibulin 5
Reactivity Human
Conjugation Unconjugated
Clonality Monoclonal
Antibody type Primary
Clone 1G6A4
Host Mouse
Isotype IgG1
Western Blot Yes
ImmunoChemistry Yes
Antigen synonyms EVEC, FLJ90059, ARMD3, DANCE, FIBL-5, UP50, FBLN5
Gene ID 10516
Format ascites
Immunogen Purified recombinant fragment of FBLN5 (aa242-448) expressed in E. Coli.
Form Liquid
Storage Buffer ascites, 0.03% sodium azide
Storage temperature Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Temperature Ice
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