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Anti-GPI Mouse Monoclonal Antibody [clone: 1B7D7]

Supplier: Thermo Scientific
MA5-15396 targets Glucose-6-phosphate isomerase in IF, IHC (P), and WB applications and shows reactivity with Human samples. The MA5-15396 immunogen is purified recombinant fragment of human GPI expressed in E. Coli. MA5-15396 detects Glucose-6-phosphate isomerase which has a predicted molecular weight of approximately 63kDa. This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.

Type: Primary
Antigen: GPI
Clonality: Monoclonal
Clone: 1B7D7
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Rat



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Size Pk VWR Catalog Number Quantity
100 µL 100 µl PIEAMA515396 Blocked
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SPECIFICATIONS

Antigen symbol GPI
Antigen name Glucose-6-phosphate isomerase
Reactivity Rat, Human
Conjugation Unconjugated
Clonality Monoclonal
Antibody type Primary
Clone 1B7D7
Host Mouse
Isotype IgG1
Western Blot Yes
ImmunoChemistry Yes
ImmunoFluorescence Yes
Flow Cytometry Yes
Antigen synonyms NLK, SA-36, PGI, AMF, GPI, GNPI, PHI
Gene ID 292804, 2821
Format ascites
Immunogen Purified recombinant fragment of human GPI expressed in E. Coli.
Form Liquid
Storage Buffer ascites, 0.03% sodium azide
Storage temperature Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Temperature Ice
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