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Anti-RAD17 Rabbit Polyclonal Antibody

Supplier: Thermo Scientific
Suggested positive control: antigen standard for RAD17 (transient overexpression lysate). Signals originating from damaged DNA activate checkpoint pathways and target the mitotic apparatus via a number a distinct mechanisms. These checkpoints link damage to DNA with the components of the cell cycle through signal transduction systems. In mammals, five genes have been identified as components of DNA damage-induced checkpoint pathways: ATM, p53, p21/WAF1/CIP1, hCHK1, and 14-3-3sigma. When overexpressed in mammalian cells, hRAD17 activates p53 and causes an accumulation of G1 phase cells, suggesting an involvement of the hRAD17 gene in this checkpoint pathway.

Type: Primary
Antigen: RAD17
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human



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Size Pk VWR Catalog Number Quantity
100 µg 100 µG PIEAPA116538 Blocked
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SPECIFICATIONS

Antigen symbol RAD17
Antigen name RAD17 homolog
Reactivity Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
Flow Cytometry Yes
Antigen synonyms Rad17 like protein, R24L, Cell cycle checkpoint protein, RAD17 homolog, Rad24, RAD17Sp, HRAD17, RF C activator 1 homolog
Gene ID 5884
Concentration 1 mg/ml
Immunogen Synthetic peptide made to a N-terminal region of human RAD 17.
Purification Antigen affinity chromatography
Form Liquid
Storage Buffer PBS, 0.01% sodium azide
Storage temperature Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Temperature Ice
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