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Anti-Tankyrase Rabbit Polyclonal Antibody

Supplier: Thermo Scientific
In Western blot, this antibody recognizes an endogenous band at ~150 kDa in whole cell extract and a band at ~180 kDa in baculovirus-derived his-tagged protein. Suggested positive control: Hela whole cell extract. The ~142 kDa Tankyrase protein is ubiquitously expressed in mammalian cells and is localized to human telomeres. It has homology to ankyrins and to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP). Tankyrase binds to TRF1 (telomeric repeat binding factor-1), which negatively regulates the maintenance of telomere length.

Type: Primary
Antigen: Tankyrase
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human



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Size Pk VWR Catalog Number Quantity
100 µL 100 µl PIEAPA116550 Blocked
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Antigen symbol Tankyrase
Antigen name Tankyrase
Reactivity Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western blot Yes
ImmunoFluorescence Yes
Antigen synonyms TNKS1, PARP5A, TIN1, TINF1, PARP-5a, pART5, PARPL
Gene ID 8658
Concentration 1 mg/ml
Immunogen A synthetic peptide made to a region of human Tankyrase within residues 250-350. The actual peptide sequence is proprietary.
Purification Antigen affinity chromatography
Form Liquid
Storage buffer tris glycine, 0.15M NaCl, 0.05% sodium azide
Storage temperature Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping temperature Ice
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