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Anti-53BP1 Rabbit Polyclonal Antibody

Supplier: Thermo Scientific
Human has been tested in WB, IHC-P and ICC/IF, mouse and goat have only been tested in ICC/IF. Suggested positive control: U205, 293T, MO59K cell lysates and MEF lysates . P53-binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double-strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.

Type: Primary
Antigen: 53BP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Goat, Human, Fish, Mouse, Primates, Rat



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Size Pk VWR Catalog Number Quantity
100 µL 100 µl PIEAPA116565 Blocked
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SPECIFICATIONS

Antigen symbol 53BP1
Antigen name Tumor suppressor p53-binding protein 1
Reactivity Fish, Rat, Human, Primates, Goat, Mouse
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoChemistry Yes
ImmunoPrecipitation Yes
ImmunoFluorescence Yes
Flow Cytometry Yes
ChIP Yes
Antigen synonyms TP53BP1, p202
Gene ID 7158, 27223
Concentration 1 mg/ml
Immunogen The epitope recognized by this antibody maps to a region between residues 350 and 400 of human tumor protein p53 binding protein 1 using the numbering given in entry NP_005648.1 (GeneID 7158).
Purification Antigen affinity chromatography
Form Liquid
Storage Buffer PBS, 0.05% sodium azide
Storage temperature 4° C, do not freeze
Shipping Temperature Ice
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