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Anti-Phospho-CREB (Ser121) Rabbit Polyclonal Antibody

Supplier: Thermo Scientific
Suggested positive control: antigen standard for CREB1 (transient overexpression lysate). Cyclic AMP Response Element Binding protein (CREB) is a basic / leucine zipper transcription factor that binds the cyclic AMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth and neurotrophic factors. CREB is also regulated by DNA-damaging stimuli and is directly phosphorylated on Ser-121 by the ataxia-telangiectasia-mutated protein kinase, ATM in response to ionizing radiation.

Type: Primary
Antigen: Phospho-CREB (Ser121)
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Mouse, Human



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Size Pk VWR Catalog Number Quantity
100 µL 100 µl PIEAPA116589 Blocked
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Antigen symbol Phospho-CREB (Ser121)
Antigen name cAMP responsive element binding protein 1
Reactivity Mouse, Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western blot Yes
ImmunoPrecipitation Yes
Antigen synonyms Active transcription factor CREB, cAMP responsive element binding protein 1, Transactivator protein, CREB1, MGC9284
Gene ID 1385, 12912
Modification Phosphorylated: Ser121
Concentration 0.3 mg/ml
Immunogen A phospho-peptide spanning the Ser-121 phosphorylation site of human CREB.
Purification Antigen affinity chromatography
Form Liquid
Storage buffer tris, 50% glycerol, 0.05% sodium azide
Storage temperature -20° C, Avoid Freeze/Thaw Cycles
Shipping temperature Ice
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