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Anti-TACR3 Rabbit Polyclonal Antibody

Supplier: Thermo Scientific
This antibody does not react with human samples and is not recommended for Western blot. The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the c-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma. Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).

Type: Primary
Antigen: TACR3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse, Rat, Ovine, Guinea Pig



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Size Pk VWR Catalog Number Quantity
150 µL 150 µl PIEAPA116714 Blocked
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SPECIFICATIONS

Antigen symbol TACR3
Antigen name Neurokinin B Receptor
Reactivity Mouse, Rat, Ovine, Guinea Pig
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
ImmunoChemistry Yes
ImmunoFluorescence Yes
Antigen synonyms NK3 receptor, Tachykinin receptor 3, TAC3RL, Neurokinin B receptor, Neuromedin K Receptor, TACR3, NK3R TAC3R
Gene ID 24808, 21338, 100135627
Format whole serum
Immunogen Raised against a synthetic peptide at the c-terminus of rat NK-3 conjugated to bovine thyroglobulin.
Form Liquid
Storage Buffer whole serum, 0.1% sodium azide
Storage temperature -20° C, Avoid Freeze/Thaw Cycles
Shipping Temperature Ice
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