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Anti-SR-BI Rabbit Polyclonal Antibody

Supplier: Thermo Scientific
Suggested positive control: antigen standard for SCARB1 (transient overexpression lysate). High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.

Type: Primary
Antigen: SR-BI
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse, Rabbit, Primates, Rat, Mink, Human, Hamster



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Size Pk VWR Catalog Number Quantity
100 µL 100 µl PIEAPA116788 Blocked
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SPECIFICATIONS

Antigen symbol SR-BI
Antigen name Scavenger receptor class B, member 1
Reactivity Mouse, Hamster, Primates, Human, Rat, Mink, Rabbit
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoChemistry Yes
ImmunoPrecipitation Yes
ImmunoFluorescence Yes
Flow Cytometry Yes
Antigen synonyms SR-B1, Scavenger Receptor-BI, SR-BI, SCARB1, Scavenger Receptor-B1
Gene ID 949, 25073, 20778
Concentration 1 mg/ml
Immunogen Synthetic peptide corresponding to a region within the residues 450-509 of mouse Scavenger Receptor-BI.
Purification Antigen affinity chromatography
Form Liquid
Storage Buffer tris citrate, 0.1% sodium azide, pH 7-8
Storage temperature 4° C, do not freeze
Shipping Temperature Ice
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