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Anti-ABCG8 Rabbit Polyclonal Antibody

Supplier: Thermo Scientific

This antibody does not react with mouse samples and is not recommended for IHC applications. ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. ABCG8, expressed at high levels in the liver and intestine, normally cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols. The mutated form of this transporter can lead to sterol accumulation and atherosclerosis or sitosterolemia, a rare autosomal recessive disorder, characterized by hyperabsorption of sterols and the inability to excrete sterols into bile.

Type: Primary
Antigen: ABCG8
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human



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Size Pk VWR Catalog Number Quantity
100 µL 100 µl PIEAPA116792 Blocked
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SPECIFICATIONS

Antigen symbol ABCG8
Antigen name ATP Binding Cassette, sub-family G, member 8
Reactivity Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
Antigen synonyms STSL, GBD4, MGC142217
Gene ID 64241
Concentration 1 mg/ml
Immunogen A synthetic peptide from the N-terminal region of human ABCG8 protein.
Purification Antigen affinity chromatography
Form Liquid
Storage Buffer PBS, 0.1% sodium azide
Storage temperature 4° C, do not freeze
Shipping Temperature Ice
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