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Anti-NUMB Rabbit Polyclonal Antibody

Supplier: Thermo Scientific
The target sequence has 90% sequence homology with rat. Numb is an evolutionarily conserved membrane-associated protein. It exists in four isoforms that differ in two functional domains: a phosphotyrosine-binding (PTB) domain and a proline-rich region (PRR). It plays a role in the control of cell fate decisions during development and antagonizes the actions of Notch. Numb proteins appear to control the self-renewal of all neural progenitor cells and could possibly play similar roles in stem-cell maintenance in other tissues.

Type: Primary
Antigen: NUMB
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Chicken, Mouse



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Size Pk VWR Catalog Number Quantity
100 µL 100 µl PIEAPA116831 Blocked
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SPECIFICATIONS

Antigen symbol NUMB
Antigen name Protein numb homolog
Reactivity Chicken, Human, Mouse
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoFluorescence Yes
Antigen synonyms Protein S171
Gene ID 8650, 18222, 395639
Concentration 3.5 mg/ml
Immunogen A synthetic peptide made to a C-terminal region of the murine numb protein sequence (between residues 600-653).
Purification Antigen affinity chromatography
Form Liquid
Storage Buffer tris glycine, 0.15M NaCl, 0.05% sodium azide
Storage temperature Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Temperature Ice
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