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Anti-Calreticulin Rabbit Polyclonal Antibody

Supplier: Thermo Scientific
PA1-16924 is specific for the ~55 kDa Calreticulin protein. There are also several reported isoforms that range from 48-62 kDa. Suggested positive control: antigen standard for CALR (transient overexpression lysate). Calreticulin is a multifunctional, highly conserved Ca2+ -binding protein that is localized to the endoplasmic reticulum (ER). It is also a molecular chaperone and is involved in protein folding events in the ER. Calreticulin has also been shown to interact with the cytoskeleton and to be involved in the regulation of gene expression. Calreticulin may play a role in cellular proliferation including its apparent activity in the proliferation of certain viruses within mammalian host cells. Recently it has been shown that calreticulin is induced in response to various types of cell stress including amino acid deprivation. Close interconnections among protein synthesis, gene expression and calcium signaling have been observed by many researchers in recent years. Calreticulin might be centrally located and crucially participate in the coordination of these functions by the cell.

Type: Primary
Antigen: Calreticulin
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse



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Size Pk VWR Catalog Number Quantity
100 µL 50 µl PIEAPA116924 Blocked
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SPECIFICATIONS

Antigen symbol Calreticulin
Antigen name Calreticulin
Reactivity Human, Mouse
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoChemistry Yes
ImmunoFluorescence Yes
Antigen synonyms CALR antibody., Autoantigen RO antibody
Gene ID 12317, 811
Format whole serum
Immunogen Full length native mouse Calreticulin protein.
Form Liquid
Storage Buffer whole serum, 0.1% sodium azide
Storage temperature Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Temperature Ice
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