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Anti-CRYAB Rabbit Polyclonal Antibody

Supplier: Thermo Scientific
This Crystallin AB antibody is useful for Western blot analysis, where a band is seen at ~20 kDa. There is also a band of greater intensity at ~40 kDa that may be an aggregated heteromeric complex. CryAB aggregates with homologous proteins, including CryAA and the small heat shock protein HSP28, to form large heteromeric complexes.Suggested positive control: human and mouse skeletal muscle lysate, human skeletal muscle protein, antigen standard for HSPB1 (transient overexpression lysate), mouse skeletal muscle protein. Crystallin AB (CryAB) is a developmentally regulated small heat shock protein known to protect cells from stress damage. It may also play an important role in the Golgi reorganization during cell division. CryAB is known to be associated with a number of neurodegenerative pathologies such as Alzheimer disease amd multiple sclerosis. As well, it has been found to be expressed in breast tumors of patients with shorter survival, suggesting that it may be a useful marker in identifying aggressive breast cancer.

Type: Primary
Antigen: CRYAB
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse



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Size Pk VWR Catalog Number Quantity
100 µL 100 µl PIEAPA116950 Blocked
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SPECIFICATIONS

Antigen symbol CRYAB
Antigen name Crystallin Alpha B
Reactivity Mouse, Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoFluorescence Yes
Antigen synonyms Alpha crystallin B chain antibody, Rosenthal fiber componet antibody, Heat-shock protein beta-5 antibod, CryAB antibody, Alpha (B)-crystallin antibody
Gene ID 1410, 12955
Concentration 1.08 mg/ml
Immunogen Synthetic peptide between amino acids 70-140 of the human Crystallin AB protein.
Purification Antigen affinity chromatography
Form Liquid
Storage Buffer tris citrate, 0.1% sodium azide, pH 7-8
Storage temperature 4° C, do not freeze
Shipping Temperature Ice
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