Anti-Caspase-3 Mouse Monoclonal Antibody [clone: C33]

Supplier: BioVision
BIOV3004-100EA 350 EUR
BIOV3004-100
Anti-Caspase-3 Mouse Monoclonal Antibody [clone: C33]
The caspase family of cysteine proteases play a key role in apoptosis. Caspase-3 is the most extensively studied apoptotic protein among caspase family members. Caspase-3 is synthesized as inactive pro-enzyme that is processed in cells undergoing apoptosis by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase-3 consists of large (17 kD) and small (12 kD) subunits which associate to form an active enzyme. The active caspase-3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells (e.g., PARP and DFF;

Recommended Dilutions: Western Blot: 0.5-4 µg/ml

Type: Primary
Antigen: Caspase-3
Clonality: Monoclonal
Clone: C33
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse, Rat
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