Anti-SREBP1 Rabbit Polyclonal Antibody

Supplier: BioVision
BIOV3961-100EA 293 EUR
Anti-SREBP1 Rabbit Polyclonal Antibody
SREBP (Sterol Regulatory Element Binding Protein) 1 and 2 are transcription factors th at regulates cholesterol homeostasis. SREBP proteins are attached to the endoplasmic reticulum and nuclear envelope. SREBP proteins undergo proteolytic cleavage in response to conditions of low cellular sterol. Upon activation of SREBP 1, a soluble NH2 cleavage fragment translocate to the nucleus and activates transcription of enzymes and other proteins required for cholesterol synthesis.

Recommended Dilutions: Western Blot: 0.5-4 µg/ml

Type: Primary
Antigen: SREBP1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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