Anti-Smac Rabbit Polyclonal Antibody

Supplier: BioVision
BIOV3298-100EA 276 EUR
Anti-Smac Rabbit Polyclonal Antibody
Smac/DIABLO is a mitochondrial protein that is released along with cytochrome c during apoptosis and activates cytochrome c/Apaf-1/caspase-9 pathway. Smac/DIABLO binds to IAPs (Inhibitor of Apoptosis Proteins) and neutralizes the inhibitory effect of IAPs. Analysis of the structural basis of Smac/DIABLO has revealed that the N-terminal amino acids are required for Smac/DIABLO to bind to IAPs and activation of caspases.

Recommended Dilutions: Western Blot: 0.5-4 µg/ml; Immunohistochemistry: 5-20 µg/ml

Type: Primary
Antigen: Smac
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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