Anti-PUMA/bbc3 Rabbit Polyclonal Antibody

Supplier: BioVision
BIOV3339R-100EA 276 EUR
Anti-PUMA/bbc3 Rabbit Polyclonal Antibody
PUMA (p53 upregulated modulator of apoptosis) is one of the pro-apoptotic Bcl-2 family members which are also transcriptional targets of p53. PUMA gene encodes two BH3 domain-containing proteins termed PUMA-α and PUMA-β. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.

Recommended Dilutions: Western Blot: 0.5-4 µg/ml; Immunohistochemistry: 5 µg/ml

Type: Primary
Antigen: PUMA/bbc3
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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