Anti-ITGA5 Recombinant Monoclonal Antibody [clone: M200]

Supplier: BioVision
BIOVA1092-200EA 705 EUR
BIOVA1092-200
Anti-ITGA5 Recombinant Monoclonal Antibody [clone: M200]
The antibody binds specifically to a5ß1 integrin, which is part of the superfamily of glycoprotein transmembrane receptors for ligands such as fibronectin, vitronectin, laminins and collagens. The a5ß1 integrin receptor plays a key role in cellular processes such as inflammation, cell proliferation, angiogenesis and tumour metastasis. Comprising the variable domain of the original mouse antibody, a chimeric mouse:human IgG4 version of this antibody has been tested in vivo: In cynomolgus monkeys with laser-induced choroidal neovascularization (CNV), in rabbit models and in human volunteers. The antibody reached Phase II clinical trials with PDL Biopharma and Biogen-Idec.

Type: Primary
Antigen: ITGA5
Clonality: Monoclonal
Clone: M200
Conjugation: Unconjugated
Epitope:
Host: Recombinant
Isotype: IgG4, kappa
Reactivity: Human
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR