Anti-Flavivirus group antigen Recombinant Monoclonal Antibody [clone: D1-4G2-4-15 (4G2)]

Supplier: BioVision
BIOVA1102-200EA 755 EUR
BIOVA1102-200
Anti-Flavivirus group antigen Recombinant Monoclonal Antibody [clone: D1-4G2-4-15 (4G2)]
Antibodies
This antibody binds to flavivirus group antigen, protein E. It can be used as an anti-Dengue virus antibody, anti-West Nile virus antibody, anti-Japanese Encephalitis or anti-Zika Virus antibody (Aubry et al. 2016) to identify cells infected with these flaviviridae. It binds to the fusion loop at the extremity of domain II of E protein from all four serotypes and prevents syncytia formation. The epitope is highly conserved amongst flaviviridae and has been functionally analyzed in detail by Crill and Chang 2004. Previous studies have used acetone- (Henchal et al. 1982) or methanol-fixed slides (Moreland & Tay, 2010). Please note that binding of this antibody has been reported to be sensitive to reduction and Western Blots should be performed under non-reducing conditions (Lai et al. 2008).

Type: Primary
Antigen: Flavivirus group antigen
Clonality: Monoclonal
Clone: D1-4G2-4-15 (4G2)
Conjugation: Unconjugated
Epitope:
Host: Recombinant
Isotype: IgG1, kappa
Reactivity: Human
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