7-Ethyl-10-hydroxycamptothecin ≥98%

Supplier: Cayman Chemical
Danger

Synonyms: SN-38(S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

CAYM15632-10EA 149 EUR
CAYM15632-10 CAYM15632-50 CAYM15632-5
7-Ethyl-10-hydroxycamptothecin ≥98%
7-Ethyl-10-hydroxycamptothecin

SN-38 is the active metabolite of irinotecan, a derivative of the alkaloid camptothecin and acts as a potent inhibitor of DNA topoisomerase I. SN-38 is a more potent topopisomerase I inhibitor and more cytotoxic to HT-29 colon cancer cells (IC50 = 8.8 nM) compared to irinotecan (IC50 >100 nM).


  • SN-38 is in a form of crystalline solid
  • λmax at 224, 267, 331, 368, 383 nm

Formula: C₂₂H₂₀N₂O₅
Storage Temperature: Freezer
MDL Number: MFCD06762720
CAS Number: 86639-52-3
UN: 2811
ADR: 6.1,III

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