Anti-SUMF1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Supplier: Bioss
BOSSBS-12366R-A647EA 858 EUR
BOSSBS-12366R-A647
Anti-SUMF1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Antibodies
SUMF1 is a 374 amino acid alternatively spliced protein that localizes to the lumen of the endoplasmic reticulum and belongs to the sulfatase-modifying factor family. Expressed ubiquitously with highest expression in liver, kidney and pancreas, SUMF1 exists as either a monomer, a homodimer or a heterodimer (with SUMF2) and functions to oxidize sulfatase cysteine residues to an active FGIy residue, thereby playing an important role in sulfatase activity. Defects in the gene encoding SUMF1 are the cause of multiple sulfatase deficiency (MSD), a heterogeneous disorder characterized by metachromatic leukodystrophy, mucopolysaccharidosis, chondrodysplasia punctata, hydrocephalus, ichthyosis, neurologic deterioration and developmental delay.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: SUMF1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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