Anti-RAGEF2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Supplier: Bioss
BOSSBS-13698R-A555EA 858 EUR
BOSSBS-13698R-A555
Anti-RAGEF2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Antibodies
RAPGEF6 is a guanine nucleotide exchange factor (GEF) that is expressed in a variety of tissues. Localizing to the cytoplasm and translocated to the plasma membrane upon ligand binding, RAPGEF6 contains an N-terminal Ras-GEF domain, a cyclic nucleotide monophosphate-binding domain, a PDZ (PSD-95/DlgA/ZO-1) domain, a Ras-associating (RA) domain and a Ras exchanger motif. RAPGEF6 is closely related to RAPGEF2 and both proteins exhibit GEF activity specific towards Rap 1 and Rap 2. In addition, RAPGEF6 is capable of binding to M-Ras via its RA domain. Due to alternative splicing events, two additional isoforms exist for RAPGEF6, namely PDZ-GEF2A and PDZ-GEF2B.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: RAGEF2
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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