Anti-CCDC69 Rabbit Polyclonal Antibody (Cy5.5®)

Supplier: Bioss
BOSSBS-6919R-CY5.5EA 505 EUR
BOSSBS-6919R-CY5.5
Anti-CCDC69 Rabbit Polyclonal Antibody (Cy5.5®)
Antibodies
The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC69 (Coiled-coil domain-containing protein 69) is a 296 amino acid protein that is encoded by a gene which maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: CCDC69
Clonality: Polyclonal
Clone:
Conjugation: Cy5.5®
Epitope:
Host: Rabbit
Isotype: IgG1
Reactivity: Human
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