Anti-TNFRSF10B Mouse Monoclonal Antibody [clone: HS201]

Supplier: ProSci
PRSI36-128EA 514 EUR
PRSI36-128
Anti-TNFRSF10B Mouse Monoclonal Antibody [clone: HS201]
Antibodies
TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.

Functional Application: Inhibition (blocks TRAIL-R2 mediated killing if applied in solution). Immunohistochemistry: (paraffin sections, 15ug/ml).

Type: Primary
Antigen: TNFRSF10B
Clonality: Monoclonal
Clone: HS201
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
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