Anti-TNFRSF10A Mouse Monoclonal Antibody [clone: TR1.02]

Supplier: ProSci
PRSI36-137EA 514 EUR
Anti-TNFRSF10A Mouse Monoclonal Antibody [clone: TR1.02]
TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.

Immunohistochemistry: (paraffin sections) (20ug/ml). Western Blot: (1ug/ml) . Optimal conditions must be determined individually for each application.

Type: Primary
Antigen: TNFRSF10A
Clonality: Monoclonal
Clone: TR1.02
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG2b
Reactivity: Human
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