Human Recombinant IL17 (from Cells)

Supplier: ProSci
PRSI91-616EA 395 EUR
PRSI91-616
Human Recombinant IL17 (from Cells)
Proteins and Peptides
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. IL-17 is also able to increase bone destruction and reduce its formation. Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation.

  • This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-6 His tag
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