Human Recombinant SHMT1 (from Cells)

Supplier: ProSci
PRSI91-687EA 580 EUR
PRSI91-687
Human Recombinant SHMT1 (from Cells)
Proteins and Peptides
Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon unit for the synthesis of methionine, thymidylate, and purines in the cytoplasm. A reduction in SHMT1 levels would result in less glycine that could affect the nervous system by acting as an agonist to the NMDA receptor and this could be a mechanism behind Smith-Magenis syndrome.

  • This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-6 His tag
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