Human Recombinant BCMO1 (from Cells)

Supplier: ProSci
PRSI91-703EA 525 EUR
Human Recombinant BCMO1 (from Cells)
Proteins and Peptides
beta , beta -Carotene 15,15'-Monooxygenase (BCMO1) is a member of the carotenoid oxygenase family. BCMO1 is highly expressed in retinal pigment epithelium, it is also expressed in the kidney, testis, liver, brain, small intestine, and colon. BCMO1 is a key enzyme in beta -carotene metabolism to vitamin A. BCMO1 catalyzes the oxidative cleavage of beta , beta -carotene into two retinal molecules. The reaction proceeds in three stages, epoxidation of the 15,15'-double bond, hydration of the double bond leading to ring opening, and oxidative cleavage of the diol formed. Defects in BCMO1 are the cause of autosomal dominant hypercarotenemia and vitamin A deficiency.

  • This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-6 His tag
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