Human Recombinant CD44 (from Cells)

Supplier: ProSci
PRSI91-888EA 395 EUR
Human Recombinant CD44 (from Cells)
Proteins and Peptides
CD44 is a cell-surface receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. A large number of CD44 isoforms can be generated by the insertion of different combinations of at least nine exons. Increased CD44 antigen is associated with relapses in non-small cell lung cancers. Furthermore, an increasing quantity of evidence suggests that CD44 has various functions related to inflammatory disease. CD44 deficiency induces severe liver injury. CD44-hyaluronate mediates in lymphocyte T and monocyte adhesion to the endothelium, stimulates proinflammatory cytokine release from macrophages and participates in dedifferentiation phenotype of smooth muscle cells from contractile state to synthetic one.

  • This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-Fc tag
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