Human Recombinant CD200 Receptor 1 (from Cells)

Supplier: ProSci
PRSI91-899EA 580 EUR
Human Recombinant CD200 Receptor 1 (from Cells)
Proteins and Peptides
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytoplasmic ITIM (immunoreceptor tyrosinebased inhibitory motif). The receptor-substrate interaction may function as a myeloid downregulatory signal.

  • This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-Fc tag
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