Human Recombinant TWEAK Receptor (from Cells)

Supplier: ProSci
PRSI91-900EA 395 EUR
Human Recombinant TWEAK Receptor (from Cells)
Proteins and Peptides
Tumor necrosis factor receptor superfamily member 12A(TNFRSF12A) is also known as Fibroblast growth factor-inducible immediate-early response protein 14, FN14, CD266 antigen and tweak-receptor. TNFRSF12A is a single-pass type I membrane protein, including a 27 aa signal peptide, a 53 aa extracellular domain, a 21 aa transmembrane domain and a 28 aa cytoplasmic domain. TNFRSF12A is highly expressed in heart, placenta and kidney. TNFRSF12A can be induced by FGF1 and phorbol ester. TNFRSF12A binds to TWEAK/TNFSF12A to initiate a signal transduction cascade, causing different cellular responses such as cell death, cell proliferation, and angiogenesis.

  • This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-Fc tag
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