Tryptases are Trypsin-like Serine Proteases. beta -Tryptases are the main isoenzymes in mast cells. beta tryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, beta -Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, beta -Tryptases are released and participate in provoking inflammatory conditions . beta -Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.
Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.