Human recombinant Isocitrate Dehydrogenase (from E. coli)

Supplier: ProSci
PRSI92-613EA 658 EUR
PRSI92-613
Human recombinant Isocitrate Dehydrogenase (from E. coli)
Enzymes
Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer, binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid.

Fusion-Tag: C-8 His tag

This recombinant protein can be used for biological assays. For research use only.
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