K. pneumoniae Recombinant Kanamycin kinase type II (from E. coli)

Supplier: ProSci
PRSI92-658EA 487 EUR
PRSI92-658
K. pneumoniae Recombinant Kanamycin kinase type II (from E. coli)
Enzymes
Aminoglycoside 3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an aminoglycoside-modifying enzyme and widely presented in resistant bacteria. These ATP-dependent enzymes phosphorylate the 3'-hydroxyl of a variety of aminoglycosides including kanamycins, neomycins, paromomycins, neamine, ribostamycin, geneticin, and paromamine. These phosphorylated aminoglycosides fail to bind to their respective ribosomal binding sites with high affinity; hence resistance is conferred to the drugs that are phosphorylated. APH(3') is primarily found in certain species of gram-positive bacteria.

This recombinant protein can be used for biological assays. For research use only.
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