Auranofin ≥98% (by NMR)Supplier: BioVision
An anti-arthritic drug that inhibits various leukocyte activation pathways at multiple sites. Inhibits release of inflammatory mediators from human basophils, pulmonary mast cells and macrophages. Efficient inducer of mitochondrial membrane permeability transition through the inhibition of mitochondrial thioredoxin reductase (TrxR).
- Inhibits human neutrophil 5-lipoxygenase
- Inhibits IκB kinase (IKK) by modifying Cys179 of the IKKß subunit
Caution: For research use only. Not for use in humans.