Guanidinium hydrochloride ≥99%, white crystalline powder for molecular biology

Supplier: MP Biomedicals
Warning

Synonyms: Guanidinium chlorideGuanidine hydrochlorideGuanidine chlorideGuanadine hydrochloride

ICNA0219482625EA 41 EUR
ICNA0219482625 ICNA0219482691 ICNA0219482680 ICNA0219482690 ICNA0219482692
Guanidinium hydrochloride ≥99%, white crystalline powder for molecular biology
Guanidinium hydrochloride

Storage: Room Temperature
Guanidine hydrochloride consists of a network of guanidinium cations and chloride anions linked by N–H•••Cl hydrogen bonds, it is a strong chaotropic agent. Guanidine HCl may agglomerate upon storage. It may appear as a free-flowing crystalline powder, a free flowing powder with solid material dispersed throughout, or a solid. The quality of the product does not appear to be affected and solutions prepared from the free-flowing and lumpy guanidine HCl appear identical.
Guanidine hydrochloride can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Also used in the isolation of RNA. Guanidine hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of protein, it can solubilize insoluble or denatured proteins such as inclusion bodies and be used for the recovery of periplasmic proteins.


  • Molecular Biology Reagent Grade
  • Presentation: White Crystalline Powder

Formula: NH₂C(=NH)NH₂·HCl
MW: 95,53 g/mol
Melting Pt: 180…190 °C
Density: 1,345 g/cm³ (20 °C) (lit.)
Storage Temperature: Ambient
MDL Number: MFCD00013026
CAS Number: 50-01-1
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Specification Test Results

Identity Test Passes
Purity ≥99%
Melting Point 180 - 190°C
FTIR Conforms to Standard
pH (6.0 M aq soln) 4-6
OD260 (6.0 M aq soln) ≤0.03
Loss on Drying ≤1.0%
Solubility (6.0 M aq soln) Clear, Colorless Solution

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