N,O-Bis(trimethylsilyl)acetamide silylation reagent, for GC derivatisationSupplier: MACHEREY-NAGEL
, Silyl Derivatisation
, Trimethylsilyl N-trimethylsilylacetamidate
BSA is a strong silylation reagent that forms very stable TMS derivatives with a large variety of compounds, e.g., non-sterically hindered alcohols, carboxylic acids, phenols, enols, steroids, (biogenic) amines and alkaloids.
- Silylation can be applied on many compounds
- Silylation reagents are easily prepared
- BSA derivatives have great volatility
Not recommended for use with carbohydrates or very low molecular weight compounds. Good solvent for polar compounds, but frequently used in combination with a solvent (pyridine, DMF etc.) or with other silylation reagents or catalysts such as TFA, HCl or TMBS. Used in combination with DMF, BSA is the reagent of choice for derivatizing phenols.
MW: 203,43 g/mol
Boiling Pt: 71–73 °C (35 mm Hg)
Density: 0,832 g/cm³ (d20°/4°)
CAS Number: 10416-59-8