N,O-Bis(trimethylsilyl)acetamide silylation reagent, for GC derivatisation

Supplier: MACHEREY-NAGEL
Danger

Synonyms: BSASilyl DerivatisationTrimethylsilyl N-trimethylsilylacetamidate

MANA701210.150EA 175 EUR
MANA701210.150 MANA701210.510 MANA701210.110
N,O-Bis(trimethylsilyl)acetamide silylation reagent, for GC derivatisation
N,O-Bis(trimethylsilyl)acetamide

BSA is a strong silylation reagent that forms very stable TMS derivatives with a large variety of compounds, e.g., non-sterically hindered alcohols, carboxylic acids, phenols, enols, steroids, (biogenic) amines and alkaloids.


  • Silylation can be applied on many compounds
  • Silylation reagents are easily prepared
  • BSA derivatives have great volatility


Not recommended for use with carbohydrates or very low molecular weight compounds. Good solvent for polar compounds, but frequently used in combination with a solvent (pyridine, DMF etc.) or with other silylation reagents or catalysts such as TFA, HCl or TMBS. Used in combination with DMF, BSA is the reagent of choice for derivatizing phenols.

Formula: C₈H₂₁NOSi₂
MW: 203,43 g/mol
Boiling Pt: 71–73 °C (35 mm Hg)
Density: 0,832 g/cm³ (d20°/4°)
MDL Number: MFCD00008270
CAS Number: 10416-59-8
UN: 3316
ADR: 9,II

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