BX-320 ≥95%

Supplier: BioVision

B2916-1EA 84.5 EUR
BX-320 ≥95%

BX-320 is an inhibitor of 3-phosphoinositide-dependent kinase-1 (PDK1). The phosphoinositide 3-kinase/PDK1/Akt signaling pathway plays an important role in cancer cell growth, survival and angiogenesis. BX-320 inhibits PDK1 enzyme activity in a kinase assay with an IC₅₀ of 30 nM. BX-320 blocks the growth of MDA-453, U87-MG and PC-3 cells in soft agar with IC₅₀ values of 0,093 μM, 0,3 μM and 0,4 μM respectively. BX-320 inhibits the growth of LOX melanoma tumors in mice models.

  • An inhibitor of PDK1

Formula: C₂₃H₃₁BrN₈O₃
MW: 547,45 g/mol
Storage Temperature: Freezer
CAS Number: 702676-93-5

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